Use
1) Naphazoline Nitrate is a sympathomimetic agent with marked alpha adrenergi activity, It is an active ingredient in several ove then counter formulations in cluding clear eys and Naphcon eye drops
2) Treating a cold allergic rhinitis, inflammatory nasal congestion, acute or chronic rhintis.
Naphazoline nitrate 5144-52-5
Items |
Standard |
Results |
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Appearance |
White or off-white powder |
White powder |
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Identification |
IR |
Exhibits maxima as that of reference standard |
Conforms |
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HPLC |
The RT of the major peak in the chromatogram of the sample corresponds to that of the reference standard, as obtained in the assay. |
Conforms |
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Loss on Drying |
≤0.5% |
0.01% |
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Residue on Ignition |
≤0.1% |
0.02% |
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Heavy Metals |
≤10ppm |
<10ppm |
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Assay(dried basis), HPLC |
98.0 ~102.0% |
101.3% |
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Related Compounds, HPLC |
Max, individual impurity ≤ 0.1% Total impurities ≤ 1.0% |
0.05% 0.24% |
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Residual Solvents, GC |
n-hexane ≤100ppm Acetone ≤3000ppm Ethyl acetate ≤1000ppm Dichloromethane ≤600ppm Chloroform ≤60ppm |
1.2ppm 55.6ppm N/D 8.7ppm N/D |
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