Application field: Alarelin acetate is a synthetic GnRH agonist.Alarelin could inhibit the gastric acid secretion both by direct actions on parietal cells in rats and by inhibiting vagous function. Alarelin could significantly enhance ratio of G1 phase and decrease ratio of S phase of GSMC of rats.
| Items | Specifications | Results |
| Appearance | White to slightly yellowish powder | White powder |
| Identity | 1167.3±1.0 | 1167.6 |
| Specific Optical Rotation | -37.0~-47.0°(C=1,1%HAc) | -41.2° |
| Amino Acid Composition | ±10% | Conforms |
| Peptide Purity (By HPLC) | ≥98% by area integration | 98.4% |
| Related Substances(By HPLC) | Total Impurities (%)≤2.0% Largest Single Impurity (%)≤ 1.0% |
1.6% 0.5% |
| Acetate Content | ≤12% | 8.8% |
| Water Content (Karl Fischer) | ≤6.0% | 4.2% |
| Peptide Content (N determination) | ≥80% | 86.5% |
| Bacterial Endotoxins | ≤15EU/mg | Conforms |
